The Relationship of Food to Disease Brought Out by Hippocrates

And this I know, moreover, that to the human body it makes a great difference whether the bread be fine or coarse; of wheat with or without the hull, whether mixed with much or little water, strongly wrought or scarcely at all, baked or raw—and a multitude of similar differences; and so, in like manner, with the cake (maza); the powers of each, too, are great, and the one nowise like the other. Whoever pays no attention to these things, or, paying attention, does not comprehend them, how can he understand the diseases which befall a man?

Hippocrates, On Ancient Medicine, vs. 14.

(Hippocrates, The Genuine Works of Hippocrates, 2 vols., trans. Francis Adams, London: Printed for the Sydenham Society, 1849, vol. 1, p. 169-170.)